Accrual to Clinical Trials (ACT)

This service is provided by the Biomedical Informatics Resource and the Trial Innovation Network Hub Liaison Team.


The Accrual to Clinical Trials (ACT) Network is a real-time platform allowing researchers to explore and validate feasibility for clinical studies across the NCATS Clinical and Translational Science Award (CTSA) consortium, from their desktops. ACT helps researchers plan and complete clinical studies, and is IRB-approved. To access the ACT platform, researchers at Columbia University may request access for themselves (see Eligibility section below), or may contact a Clinical Data Navigator in their department or by contacting us. 

ACT was developed collaboratively by members of NCATS’ Clinical and Translational Science Award (CTSA) consortium, with funding from the NIH National Center for Advancing Translational Sciences. It is based on Informatics for Integrating Biology & the Bedside (i2b2) technology, with a data sharing network software called SHRINE to enable remote queries across i2b2 installations at 40 participating CTSA sites.

The ACT application follows the i2b2 user interface. Detailed information about how to use ACT Network application is available at the ACT site where you can find tutorials, tips, and other useful information about how to navigate and effectively use the application.

Please note: a 'topic' must be selected in the Query Tool to execute a query, and we suggest you use ACT (IRB AAAR5718).


This service is available to all researchers, clinical trialists, study team members, students and faculty at Columbia University. 

The ACT network may be queried using any one of the following methods:

  1. If you have access to the iNYP application, visit, select ACT/New Account Request and follow instructions.
    1. information provided in a request is validated and access is normally granted within 7-10 days of email request. Once access is granted, the ACT query tool is available within iNYP under Explore -> ACT (i2b2) tab. Please note that a Topic must be selected in the tool to execute a query; please use ACT (IRB AAAR5718).
  2. If you do not have access to the iNYP application, you may request your departmental Clinical Data Navigator (CDN) to query the ACT network for you. See attached list to identify your departmental CDN.
  3. If you do not have a departmental CDN, the Irving Institute offers consultation with a CDN to query the ACT network for you. Visit, select the ACT/Clinical Data Navigator Service Request and follow the instructions.

When to Request This Service

This service should be requested at least one month prior to any grant or protocol submission deadlines.


There is no cost for this service.

Cite it, Submit it, Share it!

If your research has benefited from one or more Irving Institute resources, please remember to:

  • Cite our CTSA grant, UL1 TR001873, in any relevant publications, abstracts, chapters, and/or posters.
  • Submit your publications to PubMed Central (PMC) for compliance with the NIH Public Access Policy.
  • Share your research updates with us by sending an email to:


Accrual to Clinical Trials
622 West 168th Street, 10th Floor
New York, NY 10032
United States