Accrual to Clinical Trials (ACT)

This service is provided by the Biomedical Informatics Resource and the Trial Innovation Network Hub Liaison Team.


The Accrual to Clinical Trials (ACT) Network is a real-time platform allowing researchers to explore and validate feasibility for clinical studies across the NCATS Clinical and Translational Science Award (CTSA) consortium, from their desktops. ACT helps researchers plan and complete clinical studies, and is IRB-approved. To access the ACT platform, researchers at Columbia University may request access for themselves (see Eligibility section below), or may contact a Clinical Data Navigator in their department or by contacting us. 

ACT was developed collaboratively by members of NCATS’ Clinical and Translational Science Award (CTSA) consortium, with funding from the NIH National Center for Advancing Translational Sciences. It is based on Informatics for Integrating Biology & the Bedside (i2b2) technology, with a data sharing network software called SHRINE to enable remote queries across i2b2 installations at 40 participating CTSA sites.

The ACT application follows the reasonably well known i2b2 user interface. Detailed information about how to use ACT Network application is available at the ACT site where you can find tutorials, tips, and other useful information about how to navigate and effectively use the application.

Please note: a 'topic' must be selected in the Query Tool to execute a query, and we suggest you use ACT (IRB AAAR5718).


This service is available to all researchers, clinical trialists, study team members, students and faculty at Columbia University who have a Center Wide Id (CWID) and permission to access the SHRINE (i2b2) tab under Explore tab in the iNYP application.
Please note that ACT is not available with UNI authentication at present time. Please use your departmental and NYP Service Desk request processes to request for a CWID and research access into iNYP.

After a CWID is assigned and activated, please send an email request to to access ACT with the following information:

First name
Last name
Institutional email address
Reason to request access to ACT

Information provided in a request is validated and, normally, access is granted within 7-10 days of the email request. The use of the ACT application are logged and analyzed for usage analytics to monitor and improve the service. Queries may take a long time to execute and complete, and continue to run even when disconnected. Selecting a query from the ‘Previous Queries’ section reloads the results from older queries.

The system is available as is, and may experience local disruptions; it is not considered a mission critical resource. Disruptions may also occur due to problems on the site.

When to Request This Service

This service should be requested at least one month prior to any grant or protocol submission deadlines.


There is no cost for this service.

Cite it, Submit it, Share it!

If your research has benefited from one or more Irving Institute resources, please remember to:

  • Cite our CTSA grant, UL1 TR001873, in any relevant publications, abstracts, chapters, and/or posters.
  • Submit your publications to PubMed Central (PMC) for compliance with the NIH Public Access Policy.
  • Share your research updates with us by sending an email to:


Accrual to Clinical Trials
622 West 168th Street, 10th Floor
New York, NY 10032
United States