Irving Institute Announces New Multi-PI Planning Grant Awardees

The Irving Institute for Clinical and Translational Research, home to Columbia University’s Clinical and Translational Science Award (CTSA) Program hub, announces the winners of the new Irving Multi-PI Planning Grants.

The Irving Institute, in conjunction with the Columbia University Clinical Trials Office, Herbert Irving Comprehensive Cancer Center (HICCC), and the Herbert and Florence Irving Institute for Cancer Dynamics, is providing these pilot funds to support the submission of multi-component biomedical research grants (e.g. SPORE, U54, P01, P50) and large multi-PI research grants (e.g. NCATS U01, MPI grants that require NIH preapproval). The awardees are:

Epigenetic Regulation of Endogenous Retroviral DNAs and Consequences for Tumor Immunotherapy

• Stephen Goff, PhD, Biochemistry and Molecular Biophysics (Principal Investigator)
• Songtao Jia, PhD, Arts and Sciences - Biological Sciences (Co-Principal Investigator)
• Zhiguo Zhang, PhD, Pediatrics - Molecular Genetics (Co-Principal Investigator)
• Chao Lu, PhD, Genetics and Development - Genetics and Development
• Jennifer Amengual, MD, Medicine - Experimental Therapeutics

Exposomics: harmonization of high-resolution mass spectrometry for detection of exogenous chemicals in clinical research       

• Gary Miller, PhD, Environment Health Science (Principal Investigator)
• Ali Gharavi, MD, Medicine - Nephrology (Co-Principal Investigator)
• Dean Jones, PhD, Medicine
• Douglas  Walker, PhD, Environmental Medicine and Public Health
• Konstantinos Lazaridis, MD, Medicine
• Krystal Pollitt, PhD, Epidemiology

Integrated Approaches to Detect and Treat Eosinophilic Esophagitis (EoE)             

• Jianwen Que, MD, PhD, Medicine - Digestive and Liver Diseases (Principal Investigator)
• Hiroshi Nakagawa, MD PhD, Medicine - Digestive and Liver Diseases (Co-Principal Investigator)
• Julian Abrams, MD, Medicine - Digestive and Liver Diseases (Co-Principal Investigator)
• Seema Aceves, MD, PhD, Medicine - Digestive and Liver Diseases (Co-Principal Investigator)
• Dominique Bailey, MD, Pediatrics - Gastroenterology

Understanding and targeting cell-cell crosstalk in NASH-associated liver fibrosis and liver cancer

• Robert Schwabe, MD, Medicine - Digestive and Liver Diseases (Principal Investigator)
• Ira Tabas, MD, PhD, Medicine - Molecular Medicine (Co-Principal Investigator)
• Utpal Pajvani, MD, PhD, Medicine - Endocrinology (Co-Principal Investigator)

The Precision Medicine Digestive Disease Research Center           

• Timothy  Wang , MD, Medicine - Digestive and Liver Diseases (Principal Investigator)
• Kara  Gross-Margolis, MD, Pediatrics (Co-Principal Investigator)
• Howard Worman, MD, Medicine - Digestive and Liver Diseases
• Jianwen Que, MD PhD, Medicine - Digestive and Liver Diseases
• Liza Pon, PhD, Pathology and Cell Biology

Collaborative Projects in Oral Dysplasia and Carcinoma  

• Angela Yoon, DDS, MPH, MAMSc, College of Dental Medicine - Oral Pathology (Principal Investigator)
• Elizabeth Philipone, DMD, College of Dental Medicine - Oral Pathology (Co-Principal Investigator)
• Hiroshi Nakagawa, MD, PhD, Medicine - Digestive and Liver Diseases (Co-Principal Investigator)
• Richard Carvajal, MD, Medicine - Hematology and Oncology (Co-Principal Investigator)
• Gloria Su, PhD, Pathology and Cell Biology - Pathology (Co-Principal Investigator)
• Fatemeh Momen-Heravi, DDS, PhD, MPH, MS, College of Dental Medicine - Periodontics (Co-Principal Investigator)