Translational Therapeutics Accelerator Pilot Award

This service is provided by the Accelerate Resource.


The annual Translational Therapeutics Accelerator (TRx) Pilot Award is designed to provide investigators with the resources to position their therapeutic discoveries for future commercial value. The funding is awarded to therapeutic projects with the potential to impact human health. Awardees are expected to develop a commercially relevant product profile and meet targeted 12-month milestones.

The application process begins with a pre-proposal. Pre-proposals will be reviewed for eligibility and selected projects will go through the required Life Science Accelerator Boot Camp, led by experts in the field. After attending the LSA Boot Camp, the selected projects will then be eligible to submit a full pilot award application.

Duration: One (1) year

Award Amount: $75,000

Areas of Interest

Therapeutic projects in any stage of development, with a valid target and a translational/commercialization trajectory are encouraged to apply. Special consideration may be given to proposals for the development of novel therapeutics for:

  • Rare diseases originating from Precision Medicine efforts
  • Pain and addiction (e.g., management and treatment)
  • Emerging infectious diseases 
  • Diagnosis, treatment, and long-term management of long COVID-19, and
  • Unmet needs for diseases and/or public health concerns that disproportionately affect underserved communities
  • Applications from Principal Investigators and/or teams of investigators from underrepresented groups

Therapeutic strategies including small molecules, biologics, novel delivery approaches, gene therapy, and cell therapeutics will be considered.

See a list of current and past Translational Therapeutics Accelerator Pilot Award recipients.


  • The Principal Investigator of the pre-proposal application must have a full-time Columbia University faculty appointment.
  • Applicants are encouraged to apply as teams which include at least one clinician and one basic scientist.
  • To be eligible for the full pilot award, at least one member of the applicant team (including students and post-docs) must have attended the Life Sciences Accelerator Boot Camp.


The application cycle is closed. Applications open in Fall 2024. 


Cite it, Submit it, Share it!

If your research has benefited from one or more Irving Institute resources, please remember to:

  • Cite our CTSA grant, UL1 TR001873, in any relevant publications, abstracts, chapters, and/or posters.
  • Submit your publications to PubMed Central (PMC) for compliance with the NIH Public Access Policy.
  • Share your research updates with us by sending an email to:


Kayla Zalcgendler
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