Collaborative and Multidisciplinary Pilot Research – Integrating Special Populations Pilot Awardees

The Collaborative and Multidisciplinary Pilot Research - Integrating Special Populations (CaMPR-ISP) Pilot Award program focuses on the innovative assembly of new teams to gather preliminary data to address unresolved clinical, translational and public health problems with novel approaches informed by interdisciplinary and multidisciplinary collaboration. In 2019, the Irving Institute expanded the CaMPR program to include Integrating Special Populations (ISP). The CaMPR-ISP pilot awards support the formation of newly-configured investigative teams aimed at studying diseases across the lifespan and utilizing rare diseases as tools to study more common ones at Columbia University and within the community.

2022-23 CaMPR-ISP Recipients 

Light exposure and prenatal sleep: a mixed methods study of intergenerational sequelae (CaMPR-ISP) 

  • Claudia Lugo Candelas, PhD, Psychiatry – Child and Adolescent Psychiatry  (Principal Investigator) 

  • Mariana Figueiro, PhD, Light and Health Research Center, Population Health Science and Policy, Mount Sinai 

  • Maristella Lucchini, PhD, Nanit 

Mechanisms of Weight Gain After Deep Brain Stimulation Surgery for Parkinson's Disease (CaMPR-ISP) 

  • Sarah O’Shea, MD, Neurology - Aging and Dementia (Principal Investigator) 

  • Dymphna Gallagher, EdD, Medicine – Endocrinology, Institute of Human Nutrition 

  • Yunglin Gazes, PhD, Neurology  

  • Laurel Mayer, MD, Psychiatry 

  • Rajasekhar Ramakrishnan, PsyD, Irving Institute for Clinical and Translational Research 

Maternal glycemia and early childhood outcomes (MAGNET) study (CaMPR-ISP) 

  • Vidhu Thaker, MD, Pediatrics - Molecular Genetics (Principal Investigator) 

  • Noelia Zork, MD, Obstetrics and Gynecology - Maternal Fetal Medicine 

  • Dymphna Gallagher, EdD, Medicine – Endocrinology, Institute of Human Nutrition 

  • Allison Kupsco, PhD, Environment Health Science 

2021-22 CaMPR-ISP Recipients

Engraftment of human pluripotent stem cells-derived lung cells in a xenograft model

  • Nicolino Valerio Dorrello, MD, PhD, Pediatrics - Critical Care (Principal Investigator)
  • Hans-Willem Snoeck, MD, PhD, Medicine – Pulmonary (Co-Principal Investgator)
  • Hsiao-Yun Liu, PhD, Medicine – Pulmonary
  • Camilla Predella, MS, Pediatrics - Critical Care

Characterization of neuropsychiatric phenotypes and epileptiform brain activity in CHD8 haploinsufficiency

  • Rebecca Muhle, MD, PhD, Psychiatry - Child and Adolescent Psychiatry (Principal Investigator)
  • Jennifer Bain, MD, PhD, Neurology - Child Neurology
  • Sylvie Goldman, PhD, Neurology - Cognitive Neuroscience & Child Neurology and G.H. Sergievsky Center
  • Tristan Sands, MD, PhD, Neurology - Child Neurology

Determinants of zonation of liver inflammation and fibrosis in pediatric NASH

  • Jennifer Woo Baidal, MD, MPH, Pediatrics – Gastroenterology, Hepatology, and Nutrition  (Co-Principal Investigator)
  • Utpal Pajvani, MD, PhD, Medicine - Endocrinology (Co-Principal Investigator)
  • Jonathan Steinman, MD, PhD, Pediatrics - Endocrinology

Using Shared Decision Making to Increase Equitable Testing of Sexually Transmitted Infections among Adolescents and Young Adults in the Emergency Department

  • Jason Zucker, MD, MS, Medicine - Infectious Diseases (Co-Principal Investigator)
  • Lauren Chernick, MD, MSc, Emergency Medicine (Co-Principal Investigator)
  • Delivette Castor, PhD, MSc, MPH, Medicine - Infectious Diseases
  • Marc Probst, MD, MS, Emergency Medicine

2020-21 CaMPR-ISP Recipients

Safety, Feasibility and Efficacy of Stellate Ganglion Blockade on Early Posttraumatic Stress Symptoms in Cardiac Arrest Survivors: A Pilot Randomized Controlled Study (CaMPR-ISP)

  • Sachin Agarwal, MD, MPH, Neurology - Neuro ICU (Principal Investigator)
  • Ken Cheung, PhD, Biostatistics
  • Mitchell Elkind, MD, MS, Neurology
  • Maureen George, PhD, RN, AE-C, School of Nursing - Scholarship and Research
  • Ian Kronish, MH, MPH, Medicine
  • Leena Matthew, MD, Anesthesiology

Targeted Correction of X-linked HNRNPH2-related neurodevelopmental disorder (Bain Syndrome) (CaMPR-ISP)

  • Jennifer Bain, MD, PhD, Neurology - Pediatric Neurology (Principal Investigator)
  • Christopher Ricupero, PhD, College of Dental Medicine - Center for Craniofacial Regeneration (Co-Principal Investigator)
  • Barbara Corneo, MD, PhD, Rehabilitation and Regenerative Medicine - Stem Cell

Molecular pathogenesis of severe insulin resistance syndromes (CaMPR-ISP)

  • Eunhee Choi, PhD, Pathology and Cell Biology (Principal Investigator)
  • Rebecca Haeusler, PhD, Pathology and Cell Biology
  • Junhee Park, PhD, Pathology and Cell Biology

2019-20 CaMPR-ISP Recipients

High-Throughput Sequencing Platform for the Diagnosis of Bacteremia in Children with Cancer

  • Son McLaren, MD, MS, Emergency Medicine - Pediatric Emergency Medicine (Principal Investigator)
  • Peter Dayan, MD MSc, Emergency Medicine - Pediatric Emergency Medicine
  • Nischay Mishra, PhD, Epidemiology - Epidemiology
  • Nobuko Hijiya, MD, Pediatrics - Oncology-BMT-Hematology
  • Philip Zachariah, MD, MS, Pediatrics - Infectious Diseases


Telehealth After Stroke Care (TASC): Integrated multidisciplinary access to post-stroke care

  • Imama Naqvi, MD, Neurology - Stroke (Principal Investigator)
  • Sarah Tom, MPH, PhD, Epidemiology - Neurology
  • Adriana Arcia, PhD, RN, School of Nursing - Academics
  • Ying Kuen (Ken) Cheung, PhD, Biostatistics - Biostatistics
  • Olajide Williams, MD, MS, Neurology - Stroke
  • Mitchell Elkind, MD, MS, MPhil - Neurology - Stroke


Using a community-based participatory research approach to develop a culturally-tailored self-report measure to evaluate barriers and facilitators to care-seeking behavior for Parkinson''s disease among ethnic minorities

  • Hiral Shah, MD, Neurology - Movement Disorders (PI)
  • Lori Quinn, BS, MA, EdM, EdD, Teacher’s College - Health and Behavior Studies (Co-Principal Investigator)          

2019 ISP Pilot Awardees

Effects of Iron Deficiency on Early Life Immune Development

  • Thomas Connors, MD, Pediatrics (Principal Investigator)
  • Donna Farber, PhD, Surgery/Microbiology 
  • Eldad Hod, MD, PhD, Pathology and Cell Biology
  • Kalpana Pethe, MD, Pediatrics
  • Gary Brittenham, MD, Pediatrics

Interaction of OSA and APOE ε4 on Risk of Cognitive Decline

  • Nancy Kerner, MD, Psychiatry (Principal Investigator)
  • Devangere Devanand, MD, Psychiatry/Neurology
  • Terry Goldberg, PhD, Psychiatry/Anesthesiology
  • Andrew Westwood, MD, Neurology

Using Discordant Monozygotic Twins to Unlock the Genetic Basis of Aicardi Syndrome

  • Tristan Sands, MD, PhD, Neurology (Principal Investigator)
  • David Goldstein, PhD, Genetics and Development

Psychosocial Stressors and Ambulatory Blood Pressure in Young Adults with Perinatal-Acquired HIV 

  • Michael Yin, MD, MS, Medicine (Principal Investigator)
  • Stephanie Shiau, PhD, MPH, Gertrude H. Sergievsky Center
  • Stephen Arpadi, MD, MS, Gertrude H. Sergievsky Center/Pediatrics/Epidemiology
  • Jing Shen, PhD, Gertrude H. Sergievsky Center
  • Daichi Shimbo, MD, Medicine
  • Jennifer Cruz, PhD, Psychiatry 

2018 ISP Pilot Awardees

Study of Biological Aging in Young Adults with Perinatal-acquired HIV

  • Stephen M. Arpadi, MD, MS, Gertrude H. Sergievsky Center/Pediatrics/Epidemiology (Principal Investigator)
  • Stephanie Shiau, PhD, MPH, Gertrude H. Sergievsky Center
  • Michael T. Yin, MD, MS, Medicine 
  • Jing Shen, PhD, Gertrude H. Sergievsky Center
  • Louise Kuhn, PhD, MPH, MA, Gertrude H. Sergievsky Center, Epidemiology

Novel Approach to Modeling Pathogenicity of CPVT Mutations for Improving Clinical Management 

  • Oliver B. Clarke, PhD, Anesthesiology (Principal Investigator)
  • Alexander Kushnir, MD, PhD, Medicine
  • Hasan Garan, MD, Medicine
  • Andrew R. Marks, MD, Physiology and Cellular Biophysics

Analyzing Age-Related Changes of Brain Activation in Subjects Native Space

  • Qolamreza R. Razlighi, PhD, Neurology (Principal Investigator)
  • Amirreza Sedaghat, PhD, Biomedical Engineering
  • Soroush Arabshahi, PhD, Biomedical Engineering 

Metabolomic and MRI-Determined Body Composition Profile Changes Following Bariatric Surgery in Adolescents

  • Wei Shen, MD, MPH, MS, Pediatrics (Principal Investigator)
  • Ilene Fennoy, MD, Pediatrics
  • Jennifer Woo-Baidal, MD, MPH, Pediatrics
  • Jeffrey L. Zitsman, MD, Surgery

2017 ISP Pilot Awardees

  • Examining Inflammation as a Stroke Risk Factor in Pediatric Sickle Cell Disease
  • Mady Hornig, MD, MA, Epidemiology (Principal Investigator)
  • Nancy Green, MD, Pediatrics
  • Gen Li, PhD, Biostatistics
  • Margaret Lee, MD, Pediatrics
  • Philip LaRussa, MD, Pediatrics
  • Mitchel S. V. Elkind, MD, MS, Neurology

PTEN-CFTR Interactions Regulate Pulmonary Inflammation in Cystic Fibrosis - A Potential Target for Therapy

  • Alice Prince, MD, Pediatrics (Principal Investigator)
  • Sebastian Riquelme Colet, PhD, Pediatrics
  • Sarah Lusman, MD, Pediatrics
  • Wendy Chung, MD, PhD, Pediatrics
  • Emily DiMango, MD, Medicine

Factors Underlying Higher Energy Expenditure and Weight Loss in Huntington's Disease

  • Ashwini Rao, OTR, EdD, Rehabilitation and Regenerative Medicine (Principal Investigator)
  • Jacqueline Montes, Neurology, PT, EdD, NCS
  • Hiral Shah, MD, Neurology
  • Karen Marder, MD, MPH, Neurology

Rapid Genome Sequencing to Guide Clinical Management of Children With Nephrotic Syndrome

  • Simone Sanna-Cherchi, MD, Medicine (Principal Investigator)
  • Fangming Lin, MD, PhD, Pediatrics
  • Vivette D’Agati, MD, Pathology and Cell Biology
  • Vaidehi Jobanputra, PhD, MS, Pathology and Cell Biology
  • Jai Radhakrishnan, MD, MS, Medicine
  • Andrew Bomback, MD, MPH, Medicine