Irving Institute/Clinical Trials Office Pilot Awardees

The Irving Institute/Clinical Trials Office (Irving Institute/CTO) Pilot Awards are one-year clinical and translational research grants which are intended primarily for junior investigators who have not previously received funding through this mechanism.

2018 Irving Institute/CTO Pilot Awardees

  • Aditi Falnikar, PhD, Pathology and Cell Biology - Pathology: Evaluation of 7, 8 - Dihydroxyflavone, a BDNF Mimetic, as a Potential Therapeutic Agent
  • Daniel Freedberg, MD, MS, Medicine - Digestive and Liver Diseases: Dietary Fiber to Prevent Loss of Gastrointestinal Colonization Resistance and Pathogen Colonization in the Intensive Care
  • Jaime Hook, MD, Medicine - Pulmonary: Novel Mechanisms of Post-Influenza Staphylococcal Lung Injury
  • Tamar Lubell, MD, Pediatrics - Emergency Medicine - Urinary Tract Infections in Young Children: Testing a Novel, Non-Invasive, Point-of-Care Diagnostic
  • Lynn Petukhova, PhD, Dermatology - Collaboration: Initiating Translational Genetic Studies in Hidradenitis Suppurativa
  • Gissette Reyes-Soffer, MD, Medicine - Preventive Medicine: The Metabolic Effects of Lipoprotein(a) Isoforms
  • Jennifer Sumner, PhD, Medicine - Behavorial Cardiology: Developing a Biomarker-Based Metric of Biological Age in Youth
  • Hanrui Zhang, MB, PhD, Medicine - Cardiology: Discover Novel Regulators of Efferocytosis by Genome-Wide CRISPR Screen in Primary Macrophages

2017 Irving Institute/CTO Pilot Awardees

  • Juan Arriaga, PhD, Postdoctoral Research Scientist, Medicine-Hematology and Oncology: Defining Molecular Drivers and Therapeutic Strategies for Bone Metastasis by Using CRISPR/Cas9-based Functional Screening and Preclinical Assays of Drug Response
  • Amer Assal, MD, Assistant Professor, Medicine-Hematology and Oncology: Engraftment Syndrome and Acute Kidney Injury in Patients with Light Chain Amyloidosis following High Dose Chemotherapy and Autologous Stem Cell Transplantation 
  • Estibaliz Castillero, PhD, Associate Research Scientist, Surgery-Cardiothoracic Division: Bone Morphogenic protein-1 (BMP1) Proteinase in the Regulation of Cardiac Fibrosis After ischemia 
  • Deepa Kumaraiah, MD, MBA, Assistant Professor, Medicine-Cardiology: inSensor: Novel Device for Reducing Pulmonary Complications in Hospitalized Patients by Improving Compliance with Incentive Spirometer Use 
  • Martin Lan, MD, PhD, Postdoctoral Clinical Fellow, Psychiatry: Neuroinflammation as a Novel Target to Treat Bipolar Depression: A Pilot PET Study with [11C]PBR-28 and N-acetyl Cysteine Antidepressant Treatment
  • Benjamin Lebwohl, MD, MS, Assistant Professor, Medicine-Digestive and Liver Diseases: A Pilot Study to Test the Feasibility and Acceptability of Using Gluten Sensor Devices & Social Video-Based Discussion Tools to Promote a Gluten-Free Diet in Patients with Celiac Disease 
  • Matthew Lewis, MD, MPH, Assistant Professor, Medicine-Cardiology: A Precision Medicine Based Approach to Biomarker Discovery in Fontan Associated Liver Disease 
  • David Roh, MD, Assistant Professor, Neurology: The Role of Rotational Thromboelastometry (ROTEM) in Identifying Intracerebral Hemorrhage (ICH) Patients at Risk for Hematoma Expansion (HE) 
  • Ira Surolia, MD, MPH, Associate Research Scientist, Medicine-Hematology and Oncology: Investigating the Genetic and Epigenetic Basis for Anticipation in Neuroendocrine Tumors 
  • Runsheng Wang, MD, MHS, Instructor, Medicine-Rheumatology: N-of-1 Trials of Non-Steroidal Anti-Inflammatory Drugs in Spondyloarthritis with Adaptive Design

2016 Irving Institute/CTO Pilot Awardees

  • Katherine Dimitropoulou, PhD, Assistant Professor, Rehabilitation and Regenerative Medicine-Occupational Therapy: A Motor Learning Approach to Improve Motor Planning in Children with Cerebral Palsy Hemiplegia
  • Hilda Fernandez, MD, MSCE, Instructor, Medicine-Nephrology: Genomic Disorders, Chronic Kidney Disease and Neurocognitive Status in Children
  • Loren Gianini, PhD, Assistant Professor, Psychiatry, Clinical Therapeutics: Cognitive Neuroscience of Weight Loss Maintenance
  • Angela Kadenhe-Chiweshe, MD, Assistant Professor, Surgery-Pediatrics: The Role of Notch in Regulating the Response of Tumor Vasculature to High Dose Radiation
  • Omar Khalique, MD, Assistant Professor, Medicine-Cardiology: Myocardial Tissue and Functional Characterization for Prediction of Revascularization Response among patients with Coronary Arterial Chronic Total Occlusions
  • Kristen Klemenhagen, PhD, Assistant Professor, Psychiatry: Hippocampal Neurogenesis in Patients with Anxiety: a Virtual Reality-based Behavioral Study
  • Andrea Miltiades, MD, Assistant Professor, Anesthesiology: A Window into the Effects of Preeclampsia on Women’s Health Long Term: A Post-partum Longitudinal Study to Evaluate Endothelial Function and Angiogenic Biomarkers in Women Diagnosed with Early Bersus Late Onset Preeclampsia
  • Veli Topkara, MD, MSc, Assistant Professor, Medicine-Cardiology: Mitochondrial Dynamism and Autophagic Clearance Signaling Pathways in Doxorubicin Induced Cardiomyopathy
  • Nora Vanegas, MD, Assistant Professor, Neurology-Movement Disorders: White Matter Tractography Correlates of Apathy In Parkinson Disease Patients Treated with Deep Brain Stimulation
  • Constance Young, MD, Assistant Professor, Obstetrics and Gynecology, Gynecological Surgery: Assessing Activity and Recovery Following Benign Gynecologic Surgery Using Validated Tool Sets and Novel Technology: A Pilot Study
  • Min Zou, PhD, Associate Research Scientist, Medicine, Hematology and Oncology: Predicting Drug Response for Human Prostate Cancer Using a Cross-species Systems Biology Approach

2015 Irving Institute/CTO Pilot Awardees

  • Srilaxmi Bearelly, MD, MHS, Assistant Professor, Ophthalmology: Novel Ophthalmic Imaging and Genetic Approaches to Preeclampsia
  • Natalie Bello, MD, MPH, Assistant Professor, Medicine-Cardiology: The Ambulatory Blood Pressure Monitors in Pregnancy (ALPINE) Study
  • Natalie Cusano, MD, MS, Assistant Professor, Medicine-Endocrinology: The Effects of Smoking on Skeletal Microarchitecture
  • Changchun Deng, MD, PhD, Assistant Professor, Medicine-Hematology and Oncology: Novel Strategies for Targeting Myc in Aggressive Lymphoma
  • Arthur Garan, MD, Assistant Professor, Medicine-Cardiology: Pilot Study of Natriuretic Versus Standard Dose of Mineralocorticoid Receptor Antagonists in Heart Failure and Loop Diuretic Resistance
  • Jonathan Ginns, MD, Assistant Professor, Medicine: The Role of Cardiac MRI in Prediction of Postoperative Outcomes of Surgery in Isolated Chronic Aortic and Mitral Regurgitation
  • Sylvie Goldman, PhD, Assistant Professor, Neurology-Pediatrics: Motor Assessments in Children with Autism Spectrum Disorders
  • Angela Gomez-Simmonds, MD, Instructor, Medicine-Infectious Diseases: The Emergence of Carbapenem-Resistant Enterobacter Cloacae at CUMC
  • Jing Liu, MD, Associate Research Scientist, Medicine-Preventative Medicine: Hepatic Insulin Signaling Regulates ApoA-I gene Expression via Deiodinase Type I
  • Ari Shechter, PhD, Assistant Professor, Medicine-Endocrinology: Effects of Shift Work on Food Intake Regulation and Energy Expenditure
  • Nicholas J. Steers, PhD, Associate Research Scientist, Medicine-Nephrology: Defining Molecular Mechanisms of IgA1 Hyper-responsiveness and Diversity in the Pathogenesis of IgA Nephropathy
  • Emily M. Stein, MD, MD, Assistant Professor, Medicine-Endocrinology: Weight Bearing Exercise for Prevention of Bone Loss Following Bariatric Surgery: A Pilot and Feasibility Study
  • Tony J. Wang, MD, Assistant Professor, Radiation Oncology: Phase I Feasibility Trial for the Role of Cannabis in Patients With Glioblastoma Treated with Radiation and Temozolomide
  • Bin Xu, PhD, Assistant Professor, Psychiatry-Molecular Therapeutics: Exploring the Functional Impact of a Shared Rare Genetic Mutation Among Autism Patients From an Old-Order Amish population Using Human iPSC

2014 Irving Institute/CTO Pilot Awardees

  • Aditya Dutta, PhD, Associate Research Scientist, Herbert Irving Comprehensive Cancer Center: Identification Of Molecular Drivers Of Cancer Cell Adaptation To Metabolic Stress
  • Jole Fiorito, PhD, Associate Research Scientist, Medicine-Experimental Therapeutics: Treatment of Alzheimer’s Disease Using Novel Phosphodiesterase 5 Inhibitors: A Preclinical Study
  • John Gaudet Van Driest, MD, Assistant Professor, Anesthesiology: Perioperative Inflammation as a Cause of Postoperative Delirium
  • Monica Goldklang, MD, Instructor, Anesthesiology, Functional Lung Imaging in Acute Lung Injury
  • Claire Gordon, MBBS (Hons), BMedSci, Instructor, Medicine-Infectious Diseases: Identifying Tissue Reservoirs for Immune-Mediated Control of Chronic Human Herpes Viruses
  • Adam Griesemer, MD, Assistant Professor, Surgery: Combined Liver and Bone Marrow Transplantation for the Induction of Tolerance to Liver Allografts
  • David Kessler, MD, MSc, RDMS, Assistant Professor, Pediatrics-Emergency Medicine: Improving Lumbar Puncture Success in Infants Using Bedside Ultrasound: A Pilot Randomized Clinical Trial
  • Michael Kluger, MD, MPH, Assistant Professor, Surgery-GI-Endocrine: A Pilot Study to Determine the Safety of Recovered Blood Intended for Auto-transfusion During Pancreatic Cancer Operations
  • Emerson Lim, MD, MS, Assistant Professor, Medicine-Hematology and Oncology: Feasibility of Diffuse Optical Tomography (DOT) in Prostate Cancer Detection and Risk Assessment
  • Sander Markx, MD, Assistant Professor, Psychiatry-Molecular Therapeutics: Novel Treatment of Autism Spectrum Disorder Using a Compound That Targets Disease Mechanism in Patients Who Harbor Identical CNTNAP2 Mutations
  • Benjamin Ohlstein, MD, PhD, Assistant Professor, Genetics and Development: Bone Morphogenetic Protein (BMP) Regulation of Drosophila Intestinal Stem Cells
  • Maya K. Rao, MD, Assistant Professor, Medicine-Nephrology: Creating a Comprehensive Nutrition Plan in Patients with Advanced Chronic Kidney Disease: A Pilot Study
  • Carrie Shawber, PhD, Associate Research Scientist, Obstetrics and Gynecology: Characterization and Therapeutic Targeting of Lymphatic Dysfunction in Congenital Chylothorax
  • Andrew Teich, MD, PhD, Assistant Professor, Pathology and Cell Biology: An Analysis of DNA Methylation and Dementia Status in Alzheimer's Disease
  • Danielle Templeton, PhD, Postdoctoral Research Fellow, Medicine-Cardiology: Skeletal Muscle Dysfunction in Diastolic Heart Failure
  • Nina B.L. Urban, MD, MSc, Assistant Professor, Psychiatry-Substance Abuse: Deep Brain Stimulation for Refractory Alcohol Dependence

2013 Irving Institute/CTO Pilot Awardees

  • Alvaro Aytes-Meneses, PhD, Associate Research Scientist, Urology and Herbert Irving Comprehensive Cancer Center (HICCC): A Systems Biology Approach for the Identification of Molecular Drivers of Metastatic Prostate Cancer
  • Lauren Chernick, MD, Assistant Professor of Clinical Pediatrics, Pediatrics-Emergency Medicine: The Texting 2 Initiate (T2I) Study: A Pilot Randomized Controlled Trial Using Text Messaging From the Pediatric Emergency Department to Increase Contraception Initiation Amongst Adolescent Females at High Pregnancy Risk
  • Remi J. Creusot, PhD, Assistant Professor, Medicine-Immunology: Mapping Ectopic Expression of Islet Antigens in Tolerogenic Cell Subsets From Human Peripheral Lymphoid Tissues
  • Raimon Duran-Struuck, DVM, PhD, Assistant Professor, Surgery-Translational Immunology: Induction of Solid Organ Tolerance Through Bone Marrow and Regulatory T Cell Transplantation
  • Annika Hofstetter, MD, PhD, MPH, Assistant Clinical Professor, Pediatrics: A Multilevel Approach to Understanding and Optimizing Influenza and Pneumococcal Vaccination of Children with Chronic Medical Conditions
  • Ian Kronish, MD, MPH, Assistant Professor, Medicine-Behavioral Cardiology: Using Mobile Health to Improve Medication Adherence in a Social Network
  • Amir Levine, MD, Associate Research Scientist, Neuroscience: Advancing the Treatment of Pediatric Anxiety Disorders by Predicting Treatment Response Through Biocellular Markers and Sequencing Technology
  • Anthony Pinto, PhD, Assistant Professor of Clinical Psychiatry, Psychiatry-Clinical Therapeutics: Neural Mechanisms Underlying Self‐Control
  • Simone Sanna-Cherchi, MD, Associate Research Scientist, Medicine-Nephrology: Identification of Recessive Alleles Underlying Genomic Disorders of the Kidney and Urinary Tract Development
  • P. Christian Schulze, MD, PhD, Associate Professor, Medicine: Serial Analysis of Myocardial Metabolism by Positron Emissions Tomography (PET) in Patients with Heart Failure Undergoing Ventricular Assist Device Implantation
  • Markus David Siegelin, MD, Assistant Professor, Pathology and Cell Biology: Preclinical translational studies on a novel potent combined therapy for malignant glioma
  • Nadejda Tsankova, MD, PhD, Assistant Professor, Pathology and Cell Biology: Epigenetic Mechanisms of EGFR Dysregulation in Human Gliomagenesis and Glioma Progression; a Possible Role for Mutant IDH1
  • Daniel S. Tsze, MD, MPH, Assistant Professor of Clinical Pediatrics, Pediatrics-Emergency Medicine: Optimal Volumes of Administration for Intranasal Midazolam in Children
  • Raksha Urs, PhD, Associate Research Scientist, Ophthalmology: Ultrasound Microbubble Mediated Trans-Epithelial Delivery of Riboflavin for Corneal Cross-Linking Therapy
  • Elaine Wan, MD, Instructor, Medicine-Cardiology: Roles of Vascular Ion Channels in Heart Failure
  • Yanghee Woo, MD, Instructor, Surgery: Prevention and attenuation of gastric tumorogenesis through denervation

2012 Irving Institute/CTO Pilot Awardees

  • Brooke Aggarwal, EdD, MS, Associate Research Scientist, Medicine-Cardiology: A Randomized Pilot Study of an ICD/Heart Failure Patient - Family Caregiver Dyad Intervention
  • Armin Alaedini, PhD, Assistant Professor, Medicine: Proteomic Analysis of the Antibody Response in Non-Celiac Gluten Sensitivity
  • Kara L. Bickham, MD, Associate Research Scientist, Medicine: Development of Respiratory Immunity in Infants and Children
  • Angelo B. Biviano, MD, MPH, Esther Aboodi Assistant Professor of Clinical Medicine, Medicine: Utility of Atrial Electrogram Signal Analysis in Patients Undergoing Percutaneous Catheter Ablation for Atrial Fibrillation
  • Adi Cohen, MD, MHS, Assistant Professor of Clinical, Medicine: The Growth Hormone Axis and Bone Turnover in Premenopausal Women with Idiopathic Osteoporosis
  • Eileen Connolly, MD, PhD, Assistant Professor, Radiation Oncology: Enhancing the Radiation Sensitivity of Triple Negative Breast Cancer through Akt Inhibition
  • Isaac George, MD, Assistant Professor, Surgery: Dysregulation of TGF-β Family Signaling May Predict Patterns of Disease in Dilated Cardiomyopathy and Aortic Aneurysm Formation
  • Ragy R. Girgis, MD, Assistant Professor, Psychiatry-Neuroscience: The Metabotropic Glutamate Receptor 5 (mGluR 5) in Schizophrenia: A PET Study with [11C]ABP688
  • David J. Lederer, MD, MS, Herbert Irving Assistant Professor, Medicine: Obesity, Inflammation, and Lung Injury after Lung Transplantation
  • Guoxhia Liu, PhD, Associate Research Scientist, Medicine-Cardiology: Treatment of Cardiovascular Diseases Using Novel Soluble Epoxide Hydrolase Inhibitors
  • Jose Moron-Concepcion, PhD, Assistant Professor of Clinical Anesthesiology, Anesthesiology: Glial Modulators: Novel Therapeutic Interventions for Pain and Opioid Abuse
  • Kimberly Noble, MD, PhD, Assistant Professor, Pediatrics: Childhood Social Disadvantage, Brain Development, and Verbal Skills
  • Cesare Russo, MD, Associate Research Scientist, Medicine-Cardiology: Subclinical Cardiac Dysfunction, Myocardial Inflammation and Perfusion in Patients with Rheumatoid Arthritis
  • Pejman Sehatpour, PhD, Associate Research Scientist, Psychiatry: tDCS and Sensory-Perceptual Dysfunction in Schizophrenia
  • Bekir Tanriover, MD, Assistant Professor of Clinical Medicine, Medicine: Effect of Living Kidney Donation on Metabolic State and Insulin Sensitivity
  • Waichi Wong, MD, Assistant Professor of Clinical Medicine, Medicine: Is Neutropenia Post-Liver Transplant Associated with T-Cell Chimerism? A Possible Opportunity for Tolerance Induction

2011 Irving Institute/CTO Pilot Awardees

  • Susanne E. Ahmari, MD, PhD, Assistant Professor of Clinical Psychiatry, Psychiatry: Using Optogenetic Technology to Test Involvement of Orbitofrontal Cortex Pathology in Obsessive Compulsive Disorder
  • Anjali Ganda, MD, MS, Instructor in Clinical Medicine, Medicine: HDL-Mediated Cholesterol Efflux, Monocytosis, and Accelerated Atherosclerosis in Patients with Chronic Kidney Disease
  • Laura Geraldino, MD, Clinical Instructor, Medicine: Rheumatology: Anti-Citrullinated Peptide Antibodies: Surrogate Markers of Cardiac Dysfunction and/or Atherosclerosis in Rheumatoid Arthritis Patients?
  • Kevin Kalinsky, MD, Instructor in Clinical Medicine, Medicine: The Investigation of the Novel AKT Inhibitor on Magnetic Resonance Spectroscopy in Women with Operable Invasive Breast Cancer
  • Joshua Kantrowitz, MD, Assistant Professor of Clinical Psychiatry, Psychiatry: NMDA and Cognitive Remediation in Schizophrenia
  • Krzysztof Kiryluk, MD, MS, Instructor in Clinical Medicine, Medicine: Genetic Causes of IgA Nephropathy by Next Generation Sequencing
  • David K. Leung, MD, PhD, Assistant Professor of Clinical Radiology, Radiology: Functional Imaging in Pancreatic Cancer: Investigations of a New Tumor Specific PET Radiotracer
  • Julian Mackay-Wiggan, MD, MS, Assistant Clinical Professor, Dermatology: A Randomized Placebo Controlled Study of IL Triamcinolone Acetonide in the Treatment of Alopecia Areata and Investigation of Biomarkers in Patients with Alopecia Areata
  • Catherine Monk, PhD, Assistant Professor of Clinical Psychology, Psychiatry: Electrophysiological Development in Toddlers of Adolescent Mothers: Association with Maternal Antenatal Stress and Nutrition
  • John P. Morrow, MD, Assistant Professor, Medicine-Cardiology: PKG Activation to Protect Against Arrhythmias in Animal Models of LQTS and Diabetic Cardiomyopathy
  • Gabrielle Page-Wilson, MD, Instructor, Medicine: Treatment of Hyperprolactinemia with the Non-Ergoline Dopamine Agonist Ropinirole - A Dose Escalation Study of Efficacy and Tolerability
  • Paul J. Planet, MD, PhD, Postdoctoral Clinical Fellow, Pediatrics: Adaptation of MRSA to Ethanol-Based Microbicides: Impact of a Novel Alcohol Dehydrogenase (AdhC) on Epidemiology and Virulence
  • Tara M. Randis, MD, Assistant Professor, Pediatrics: New Approaches to Prevention of Neonatal Group B Streptococcal Disease
  • Igor Shuryak, MD, PhD, Associate Research Scientist, Center for Radiological Research: Low Dose Prophylactic Mammary Irradiation to Reduce Contralateral Second Breast Cancer Risks
  • Douglas M. Sproule, MD, Instructor, Neurology: Body Composition, Nutrition and Energy Utilization in Spinal Muscular Atrophy
  • Anette Wu, MD, MPH, Associate Research Scientist, Medicine-Oncology: Induction of Liver Allograft Tolerance through Bone Marrow Transplantation: Translational Pre-clinical Pilot Study in Monkeys

2010 Irving Institute/CTO Pilot Awardees

  • Julian Abrams, MD, MS, Assistant Professor of Clinical Medicine, Medicine: Digestive and Liver Diseases, Use of a Gastrin-Receptor Antagonist for Chemoprevention in Patients with Barrett's Esophagus
  • Emilio Arteaga-Solis, MD, PhD, Assistant Professor, Pediatrics: A Mechanistic Link of Obesity-Associated Asthma: Leptin Mediates Lung Physiology via a Central Nervous System Relay
  • Gudrun Aspelund, MD, Assistant Professor, Surgery: Interval Appendectomy Compared with Nonoperative Treatment for Perforated Appendicitis in Children
  • Jae H. Choi, MD, MS, Assistant Professor, Neurology: Non-Invasive Quantification of Cerebral Autoregulation in Patients with Acute Ischemic Stroke and Increased Risk for Ischemic Stroke
  • Christoph Kellendonk, PhD, Assistant Professor of Pharmacology, Psychiatry: A Translational Study: Methylphenidate Effects on Frontostriatal Circuits in ADHD
  • Laura B. McIntire, PhD, Associate Research Scientist, Pathology and Cell Biology: In Vivo Efficacy of a New Class of CNS Targeted Amyloid Lowering Compounds
  • Jose F. Morales, PhD, Associate Research Scientist, Joint Center for System Biology: The Lymphoid Malignancy Phenome Score
  • Nicholas J. Morrissey, MD, Assistant Professor, Surgery, Assessment of Vascular Disease Frequency, Risk Factors, and Outcomes in Hispanic Patients
  • Andrew B. Munkacsi, PhD, Associate Research Scientist, Pediatrics: Inhibition of Histone Deacetylase as a Treatment of Neurodegeneration and Defective Cholesterol Transport in Niemann-Pick Type C Disease
  • Hatice Duygu Onat, PhD, Associate Research Scientist, Medicine: Type 2 Diabetes and Vascular Disease in Human Studies: The Interplay of Systemic Endothelial Activation and Inflammatory Cell Stress During Disease Progress
  • David C. Riley, MD, MS, Assistant Clinical Professor of Medicine, Medicine: Emergency Department Real Time Cannulation of the Internal Jugular Vein on the First Attempt: Ultrasound-Guided Short-Axis vs. Long-Axis Method
  • P. Christian Schulze, MD, PhD, Assistant Professor, Medicine: Effects of Glutamine and Fish Oil on Muscle Function in Heart Failure (GlutFish-HF)
  • Aviva Bracha Sopher, MD, MS, Postdoctoral Clinical Fellow, Pediatrics: Body Composition and Metabolic Manifestations of Insulin Resistance in Adolescents with Polycystic Ovary Syndrome: Ectopic Fat Deposition and Metabolic Markers
  • Krishna Surapaneni, MD, MPH, Postdoctoral Clinical Fellow, Radiology: In Vivo MRI Immune Cell Tracking and Quantification of Target Natural Killer (NK) Cell Immunotherapy for Poor Risk Childhood B-Cell (CD20+) Lymphoma/Leukemia
  • Arun Swaminath, MD, Assistant Professor of Clinical Medicine, Medicine-Digestive and Liver Diseases: The Use of Positron Emission Tomography, Inflammatory Makers, and Intestinal Stem Cell Concentration to Predict Response to Treatment of Small Bowel Crohn's Disease with Biologic Therapy: A Pilot Study
  • Edward Thorp, PhD, Associate Research Scientist, Medicine: Soluble MER in CVD

2009 Irving Insitute/CTO Pilot Awardees

  • Jason B. Carmel, MD, PhD, Instructor, Neurology: Transcranial Direct Current Stimulation to Strengthen Corticospinal Connections and Promote Recovery After Injury
  • Neil R. Gleason, MD, Instructor, Anesthesiology: GABAa Receptors on Human Vascular Smooth Muscle Influence Blood Pressure
  • Kara J. Gross, MD, Assistant Professor, Pediatrics: Serotonin Depletion in the Prevention and Treatment of Inflammatory Bowel Diseases and Necrotizing Enterocolitis
  • Anupam B. Kharbanda, MD, Assistant Professor of Clinical Pediatrics, Pediatrics-Emergency Medicine: Biomarker Profiling for Pediatric Appendicitis
  • Judith Korner, MD, PhD, Associate Professor of Medicine, Medicine: Changes in Gut Hormones and Neural Control of Food Intake in Hypothalamic Obesity
  • Antonio Mantovani, MD, PhD, Associate Research Scientist, Psychiatry: Modulation of Premotor and Motor Circuits in Obsessive-Compulsive Disorder (OCD): A Transcranial Magnetic Stimulation (TMS) and Magnetic Resonance Spectroscopy (MRS) Study
  • Igor Matushansky, MD, PhD, Assistant Professor of Medicine, Medicine: Oncology, Implementing and Imaging Epigenetic Based Differentiation Therapy for Solid Tumors
  • June Wu, MD, Assistant Professor of Surgery, Surgery: The Role of Notch3 Signaling in the Pathogenesis of Hemangiomas

2008 Irving Institute/CTO Pilot Awardees

  • Hyunmi Choi, MD, MS, Assistant Professor of Clinical Neurology, Neurology: The Role of Coenzyme Q10 in Pathogenesis and Therapy of Intractable Temporal Lobe Epilepsy with Hippocampal Sclerosis
  • Jan Claassen, MD, PhD, Assistant Professor, Neurology: Impact of Electrographic Seizures and Periodic Epileptiform Patterns on Neuronal Function and Outcome in Brain Injured Patients
  • Raphael Clynes, MD, PhD, Assistant Professor of Medicine, Medicine: Induction of Tumor Immunity in Untreated CLL Patients Through the Use of Rituximab and Denileukin Diftitox
  • Charles J. DiMaggio, PhD, Assistant Professor of Clinical Epidemiology, Anesthesiology: Retrospective Cohort Analysis of the Effects of Anesthesia on Behavioral and Developmental Disorders in Young Children
  • Barry Hudson, PhD, Associate Research Scientist, Surgery: Preoncology: The Soluble Splice Variant of RAGE is a Protective Mechanism Against Tumorigenesis and Metastasis
  • Daniel Kass, MD, Instructor in Clinical Medicine, Medicine: Targeting the MetAP2 Pathway in Pulmonary Arterial Hypertension
  • Marilyn Morris, MD, MPH, Assistant Professor of Clinical Pediatrics, Clinical Care - Ethics: Pediatric Minimal Risk Research: A Parental Perspective
  • David Paik, MD, Associate Research Scientist, Ophthalmology: Development of a Pharmacologic Alternative to Therapeutic Corneal Cross-Linking Using Aliphatic Beta-Nitro Alcohols (Proprietary Columbia University Technology)
  • Gissette Reyes, MD, Instructor, Medicine: Preventive Medicine and Nutrition: Lipoprotein Metabolism in Obese Postmenopausal Metabolically Healthy Obese Versus Metabolically Abnormal Obese Women
  • Mishaela Rubin, MD, Assistant Professor of Clinical Medicine, Medicine: Endocrinology, Osteocalcin and Glucose Homeostasis in Hypoparathyroidism
  • Bret Rutherford, MD, Postdoctoral Clinical Fellow, Pediatrics: Expectancy Effects and Treatment of Depression: Cognitive and Neural Mechanisms
  • Aaron Turkish, MD, Assistant Professor of Pediatrics, Pediatrics-Developmental Drugs: Development of a Novel Murine Model of Skin Disease

2007 Irving Institute/CTO Pilot Awardees

  • Richard C. E. Anderson, MD, Assistant Professor of Neurological Surgery, Neurology: Identification of CD24 as a Target for Antibody-Based Immunotherapy for Pediatric Medulloblastoma
  • Raphael Clynes, MD, PhD, Assistant Professor of Medicine, Medicine, Converting Passive to Active Immunity: Correlation of HER-2 Specific T Cell Responses and Clinical Outcomes in Patients Treated with Traztuzumab
  • Andrew Einstein, MD, PhD, Assistant Professor of Clinical Medicine, Medicine: Cardiology, Effects of Patient Habitus and Breast Shielding on Radiation Dose in Coronary Computed Tomography Angiography
  • Charles W. Emala, MD, Associate Professor, Anesthesiology: GABAa- Mediated Relaxation of Airway Smooth Muscle
  • Adolfo Ferrando, MD, PhD, Assistant Professor of Pediatrics and Pathology, Pediatrics: Treatment of T-ALL with Gamma-Secretase Inhibitors
  • Ali Gharavi, MD, Assistant Professor, Medicine: Genetic Studies of Acute Renal Allograft Rejection
  • Seunghee Kim-Schulze, PhD, Associate Research Scientist, Surgery: Targeting Inhibitory Receptor ILT3 in Immunotherapy
  • Robert Klitzman, MD, Associate Professor of Clinical Psychiatry, Sociomedical Sciences: Views and Approaches Toward Pre-Implantation Genetic Diagnosis (PGD) and Barriers to its Use Among Providers and Patients
  • Laurel Mayer, MD, Irving Assistant Professor, Psychiatry: Understanding the Neural Circuitry of Eating Disorders
  • Arielle D. Stanford, MD, Assistant Professor of Clinical Psychiatry, Psychiatry: Delineating and Modulating the Circuitry of Volition: Treatment Development in Schizophrenia
  • Drew V. Tortoriello, MD, Assistant Professor, Obstetrics and Gynecology: Long-acting Mullerian Inhibiting Substance Analogue for the Treatment of Endometriosis
  • Qin Wang, PhD, Assistant Professor of Clinical Pathology, Surgery: Endothelial Cell Injury During High Dose IL-2 Immunotherapy
  • William Whang, MD, MS, Assistant Professor of Clinical Medicine, Medicine: Cardiology, Pilot Studies of Ventricular Remodeling, Microvolt t-wave Alternans and Sudden Cardiac Death
  • Ismee Williams, MD, MS, Assistant Professor of Clinical Pediatrics, Pediatrics: Endocrinology, The Impact of Congenital Heart Disease on Fetal and Neonatal Neurologic Structure and Function
  • Michael Yin, MD, MS, Assistant Professor of Clinical Medicine, Medicine-Infectious Diseases: Development and Validation of a Multiplex PCR Assay for Rapid Diagnosis of Ventriculostomy Related Infections
  • Yi-Hao Yu, MD, PhD, Assistant Professor, Medicine: Using Dietary Leucine Supplementation to Modify Cardiometabolic Risk Factors in Overweight and Obese Adult Human Subjects