Irving Multi-PI Planning Grant Awardees

The Irving Institute, in conjunction with the Columbia University Clinical Trials Office, and Herbert Irving Comprehensive Cancer Center (HICCC), offers the Irving Multi-PI Planning Grants to support the submission of multi-component biomedical research grants (e.g. SPORE, U54, P01, P50) and large multi-PI research grants (e.g. NCATS U01, MPI grants that require NIH preapproval).

2021-2022 Irving Multi-PI Planning Grant Awardees

Prospective Genetic Risk, Emergence, and Pre-Symptomatic Intervention for Autism Spectrum Disorder

  • Wendy Chung, MD, PhD, Pediatrics - Clinical Genetics (Principal Investigator)
  • Jeremy Veenstra-VanderWeele, MD, Psychiatry - Child and Adolescent (Co-Principal Investigator)
  • Dima Amso, PhD, Psychology
  • Paul Applebaum, MD, Psychiatry - Mental Health Service Research and Policy 
  • Jennifer Bain, MD, PhD, Neurology – Child Neurology
  • William Fifer, PhD, Psychiatry - Developmental Neuroscience 
  • Sylvie Goldman, PhD, Neurology – Child Neurology
  • Stephen Kanne, PhD, Weill Cornell Medical College
  • So Hyun Kim, PhD, Weill Cornell Medical College
  • Matthew Lebowitz, PhD, Psychiatry – Mental Health Service Research and Policy
  • Rebecca Muhle, MD, PhD, Psychiatry – Child and Adolescent and Developmental Neuroscience
  • Anna Penn, MD, PhD, Pediatrics - Neonatology
  • Yufeng Shen, PhD, Systems Biology and Biomedical Informatics
  • Kally Sparks, PhD, Psychiatry – Child and Adolescent
  • Dennis Vitkup, PhD, Systems Biology and Biomedical Informatics
  • Chaolin Zhang, PhD, Systems Biology and Biochemistry and Molecular Biophysics 

 

Epigenetic remodeling, emergency myelopoiesis and stromal cell signaling-induced stem cell reprograming in AML transformation

  • Stavroula Kousteni, PhD, Physiology – Research (Principal Investigator)
  • Emmanuel Passegue, PhD, Genetics and Development (Co-Principal Investigator)
  • Adolfo Ferrando, MD, Pediatrics (Co-Principal Investigator)
  • Jellert Gaublomme, PhD, Arts and Sciences - Biological Sciences
  • Raul Rabadan, PhD, Biomedical Informatics

 

Center for Intergenerational Psychiatry

  • Jonathan Posner, MD, Psychiatry - Child and Adolescent (Principal Investigator)
  • Cristiane Duarte, PhD, MPH, Psychiatry - Child and Adolescent (Co-Principal Investigator)
  • Christoph Anacker, PhD, Psychiatry – Systems Neuroscience
  • Andrea Baccarelli, MD, PhD, MPH, Environmental Health Sciences
  • Catherine Monk, PhD, Obstetrics and Gynecology – Research
  • Myrna Weissman, PhD, MSW, Psychiatry and Epidemiology

 

Investigating cell-intrinsic and extrinsic interactions in prostate cancer at the single-cell level

  • Michael Shen, PhD, Medicine - Hematology and Oncology (Principal Investigator)
  • Cory Abate-Shen, PhD, Molecular Pharmacology and Therapeutics (Co-Principal Investigator)

 

Translating Rare Disease Discoveries into Improved Care via a Learning Health System

  • Chunhua Weng, PhD, Biomedical Informatics (Principal Investigator)
  • Paul Applebaum, MD, Psychiatry - Mental Health Service Research and Policy (Co-Principal Investigator)
  • Wendy Chung, MD, PhD, Pediatrics - Clinical Genetics (Co-Principal Investigator)
  • Cong Liu, PhD, Biomedical Informatics (Co-Principal Investigator)
  • George Hripcsak, MD, Biomedical Informatics
  • Rachel Lewis, MD, Pediatrics

 

2020-2021 Irving Multi-PI Planning Grant Awardees

Epigenetic Regulation of Endogenous Retroviral DNAs and Consequences for Tumor Immunotherapy

  • Stephen Goff, PhD, Biochemistry and Molecular Biophysics (Principal Investigator)
  • Songtao Jia, PhD, Arts and Sciences - Biological Sciences (Co-Principal Investigator)
  • Zhiguo Zhang, PhD, Pediatrics - Molecular Genetics (Co-Principal Investigator)
  • Chao Lu, PhD, Genetics and Development - Genetics and Development
  • Jennifer Amengual, MD, Medicine - Experimental Therapeutics

Exposomics: harmonization of high-resolution mass spectrometry for detection of exogenous chemicals in clinical research         

  • Gary Miller, PhD, Environment Health Science (Principal Investigator)
  • Ali Gharavi, MD, Medicine - Nephrology (Co-Principal Investigator)
  • Dean Jones, PhD, Medicine
  • Douglas  Walker, PhD, Environmental Medicine and Public Health
  • Konstantinos Lazaridis, MD, Medicine
  • Krystal Pollitt, PhD, Epidemiology

Integrated Approaches to Detect and Treat Eosinophilic Esophagitis (EoE)             

  • Jianwen Que, MD, PhD, Medicine - Digestive and Liver Diseases (Principal Investigator)
  • Hiroshi Nakagawa, MD PhD, Medicine - Digestive and Liver Diseases (Co-Principal Investigator)
  • Julian Abrams, MD, Medicine - Digestive and Liver Diseases (Co-Principal Investigator)
  • Seema Aceves, MD, PhD, Medicine - Digestive and Liver Diseases (Co-Principal Investigator)
  • Dominique Bailey, MD, Pediatrics - Gastroenterology

Understanding and targeting cell-cell crosstalk in NASH-associated liver fibrosis and liver cancer

  • Robert Schwabe, MD, Medicine - Digestive and Liver Diseases (Principal Investigator)
  • Ira Tabas, MD, PhD, Medicine - Molecular Medicine (Co-Principal Investigator)
  • Utpal Pajvani, MD, PhD, Medicine - Endocrinology (Co-Principal Investigator)

The Precision Medicine Digestive Disease Research Center           

  • Timothy  Wang , MD, Medicine - Digestive and Liver Diseases (Principal Investigator)
  • Kara  Gross-Margolis, MD, Pediatrics (Co-Principal Investigator)
  • Howard Worman, MD, Medicine - Digestive and Liver Diseases
  • Jianwen Que, MD PhD, Medicine - Digestive and Liver Diseases
  • Liza Pon, PhD, Pathology and Cell Biology

Collaborative Projects in Oral Dysplasia and Carcinoma  

  • Angela Yoon, DDS, MPH, MAMSc, College of Dental Medicine - Oral Pathology (Principal Investigator)
  • Elizabeth Philipone, DMD, College of Dental Medicine - Oral Pathology (Co-Principal Investigator)
  • Hiroshi Nakagawa, MD, PhD, Medicine - Digestive and Liver Diseases (Co-Principal Investigator)
  • Richard Carvajal, MD, Medicine - Hematology and Oncology (Co-Principal Investigator)
  • Gloria Su, PhD, Pathology and Cell Biology - Pathology (Co-Principal Investigator)
  • Fatemeh Momen-Heravi, DDS, PhD, MPH, MS, College of Dental Medicine - Periodontics (Co-Principal Investigator)