Irving Institute/Clinical Trials Office Pilot Awardees

This one-year research grant focused primarily on junior investigators who had not previously received funding through the Clinical Trials Office. Our Pilot and Collaborative Studies Resource currently offers several funding opportunities for clinical and translational research initiatives, including pilot awards to junior investigators and grants in support of clinical and translational research and methodology.

2018 Irving Institute/CTO Pilot Awardees

  • Aditi Falnikar, PhD, Pathology and Cell Biology - Pathology: Evaluation of 7, 8 - Dihydroxyflavone, a BDNF Mimetic, as a Potential Therapeutic Agent
  • Daniel Freedberg, MD, MS, Medicine - Digestive and Liver Diseases: Dietary Fiber to Prevent Loss of Gastrointestinal Colonization Resistance and Pathogen Colonization in the Intensive Care
  • Jaime Hook, MD, Medicine - Pulmonary: Novel Mechanisms of Post-Influenza Staphylococcal Lung Injury
  • Tamar Lubell, MD, Pediatrics - Emergency Medicine - Urinary Tract Infections in Young Children: Testing a Novel, Non-Invasive, Point-of-Care Diagnostic
  • Lynn Petukhova, PhD, Dermatology - Collaboration: Initiating Translational Genetic Studies in Hidradenitis Suppurativa
  • Gissette Reyes-Soffer, MD, Medicine - Preventive Medicine: The Metabolic Effects of Lipoprotein(a) Isoforms
  • Jennifer Sumner, PhD, Medicine - Behavorial Cardiology: Developing a Biomarker-Based Metric of Biological Age in Youth
  • Hanrui Zhang, MB, PhD, Medicine - Cardiology: Discover Novel Regulators of Efferocytosis by Genome-Wide CRISPR Screen in Primary Macrophages

2017 Irving Institute/CTO Pilot Awardees

  • Juan Arriaga, PhD, Postdoctoral Research Scientist, Medicine-Hematology and Oncology: Defining Molecular Drivers and Therapeutic Strategies for Bone Metastasis by Using CRISPR/Cas9-based Functional Screening and Preclinical Assays of Drug Response
  • Amer Assal, MD, Assistant Professor, Medicine-Hematology and Oncology: Engraftment Syndrome and Acute Kidney Injury in Patients with Light Chain Amyloidosis following High Dose Chemotherapy and Autologous Stem Cell Transplantation 
  • Estibaliz Castillero, PhD, Associate Research Scientist, Surgery-Cardiothoracic Division: Bone Morphogenic protein-1 (BMP1) Proteinase in the Regulation of Cardiac Fibrosis After ischemia 
  • Deepa Kumaraiah, MD, MBA, Assistant Professor, Medicine-Cardiology: inSensor: Novel Device for Reducing Pulmonary Complications in Hospitalized Patients by Improving Compliance with Incentive Spirometer Use 
  • Martin Lan, MD, PhD, Postdoctoral Clinical Fellow, Psychiatry: Neuroinflammation as a Novel Target to Treat Bipolar Depression: A Pilot PET Study with [11C]PBR-28 and N-acetyl Cysteine Antidepressant Treatment
  • Benjamin Lebwohl, MD, MS, Assistant Professor, Medicine-Digestive and Liver Diseases: A Pilot Study to Test the Feasibility and Acceptability of Using Gluten Sensor Devices & Social Video-Based Discussion Tools to Promote a Gluten-Free Diet in Patients with Celiac Disease 
  • Matthew Lewis, MD, MPH, Assistant Professor, Medicine-Cardiology: A Precision Medicine Based Approach to Biomarker Discovery in Fontan Associated Liver Disease 
  • David Roh, MD, Assistant Professor, Neurology: The Role of Rotational Thromboelastometry (ROTEM) in Identifying Intracerebral Hemorrhage (ICH) Patients at Risk for Hematoma Expansion (HE) 
  • Ira Surolia, MD, MPH, Associate Research Scientist, Medicine-Hematology and Oncology: Investigating the Genetic and Epigenetic Basis for Anticipation in Neuroendocrine Tumors 
  • Runsheng Wang, MD, MHS, Instructor, Medicine-Rheumatology: N-of-1 Trials of Non-Steroidal Anti-Inflammatory Drugs in Spondyloarthritis with Adaptive Design

2016 Irving Institute/CTO Pilot Awardees

  • Katherine Dimitropoulou, PhD, Assistant Professor, Rehabilitation and Regenerative Medicine-Occupational Therapy: A Motor Learning Approach to Improve Motor Planning in Children with Cerebral Palsy Hemiplegia
  • Hilda Fernandez, MD, MSCE, Instructor, Medicine-Nephrology: Genomic Disorders, Chronic Kidney Disease and Neurocognitive Status in Children
  • Loren Gianini, PhD, Assistant Professor, Psychiatry, Clinical Therapeutics: Cognitive Neuroscience of Weight Loss Maintenance
  • Angela Kadenhe-Chiweshe, MD, Assistant Professor, Surgery-Pediatrics: The Role of Notch in Regulating the Response of Tumor Vasculature to High Dose Radiation
  • Omar Khalique, MD, Assistant Professor, Medicine-Cardiology: Myocardial Tissue and Functional Characterization for Prediction of Revascularization Response among patients with Coronary Arterial Chronic Total Occlusions
  • Jin Hee Kim, MD, Assistant Professor, Obstetrics and Gynecology: Assessing Activity and Recovery Following Benign Gynecologic Surgery Using Validated Tool Sets and Novel Technology: A Pilot Study
  • Andrea Miltiades, MD, Assistant Professor, Anesthesiology: A Window into the Effects of Preeclampsia on Women’s Health Long Term: A Post-partum Longitudinal Study to Evaluate Endothelial Function and Angiogenic Biomarkers in Women Diagnosed with Early Bersus Late Onset Preeclampsia
  • Helen B. Simpson, MD, PhD, Professor, Psychiatry: Hippocampal Neurogenesis in Patients with Anxiety: a Virtual Reality-based Behavioral StudyVeli Topkara, MD, MSc, Assistant Professor, Medicine-Cardiology: Mitochondrial Dynamism and Autophagic Clearance Signaling Pathways in Doxorubicin Induced Cardiomyopathy
  • Nora Vanegas, MD, Assistant Professor, Neurology-Movement Disorders: White Matter Tractography Correlates of Apathy In Parkinson Disease Patients Treated with Deep Brain Stimulation
  • Min Zou, PhD, Associate Research Scientist, Medicine, Hematology and Oncology: Predicting Drug Response for Human Prostate Cancer Using a Cross-species Systems Biology Approach

2015 Irving Institute/CTO Pilot Awardees

  • Srilaxmi Bearelly, MD, MHS, Assistant Professor, Ophthalmology: Novel Ophthalmic Imaging and Genetic Approaches to Preeclampsia
  • Natalie Bello, MD, MPH, Assistant Professor, Medicine-Cardiology: The Ambulatory Blood Pressure Monitors in Pregnancy (ALPINE) Study
  • Natalie Cusano, MD, MS, Assistant Professor, Medicine-Endocrinology: The Effects of Smoking on Skeletal Microarchitecture
  • Changchun Deng, MD, PhD, Assistant Professor, Medicine-Hematology and Oncology: Novel Strategies for Targeting Myc in Aggressive Lymphoma
  • Arthur Garan, MD, Assistant Professor, Medicine-Cardiology: Pilot Study of Natriuretic Versus Standard Dose of Mineralocorticoid Receptor Antagonists in Heart Failure and Loop Diuretic Resistance
  • Jonathan Ginns, MD, Assistant Professor, Medicine: The Role of Cardiac MRI in Prediction of Postoperative Outcomes of Surgery in Isolated Chronic Aortic and Mitral Regurgitation
  • Sylvie Goldman, PhD, Assistant Professor, Neurology-Pediatrics: Motor Assessments in Children with Autism Spectrum Disorders
  • Angela Gomez-Simmonds, MD, Instructor, Medicine-Infectious Diseases: The Emergence of Carbapenem-Resistant Enterobacter Cloacae at CUMC
  • Jing Liu, MD, Associate Research Scientist, Medicine-Preventative Medicine: Hepatic Insulin Signaling Regulates ApoA-I gene Expression via Deiodinase Type I
  • Ari Shechter, PhD, Assistant Professor, Medicine-Endocrinology: Effects of Shift Work on Food Intake Regulation and Energy Expenditure
  • Nicholas J. Steers, PhD, Associate Research Scientist, Medicine-Nephrology: Defining Molecular Mechanisms of IgA1 Hyper-responsiveness and Diversity in the Pathogenesis of IgA Nephropathy
  • Emily M. Stein, MD, MD, Assistant Professor, Medicine-Endocrinology: Weight Bearing Exercise for Prevention of Bone Loss Following Bariatric Surgery: A Pilot and Feasibility Study
  • Tony J. Wang, MD, Assistant Professor, Radiation Oncology: Phase I Feasibility Trial for the Role of Cannabis in Patients With Glioblastoma Treated with Radiation and Temozolomide
  • Bin Xu, PhD, Assistant Professor, Psychiatry-Molecular Therapeutics: Exploring the Functional Impact of a Shared Rare Genetic Mutation Among Autism Patients From an Old-Order Amish population Using Human iPSC

2014 Irving Institute/CTO Pilot Awardees

  • Aditya Dutta, PhD, Associate Research Scientist, Herbert Irving Comprehensive Cancer Center: Identification Of Molecular Drivers Of Cancer Cell Adaptation To Metabolic Stress
  • Jole Fiorito, PhD, Associate Research Scientist, Medicine-Experimental Therapeutics: Treatment of Alzheimer’s Disease Using Novel Phosphodiesterase 5 Inhibitors: A Preclinical Study
  • Monica Goldklang, MD, Instructor, Anesthesiology, Functional Lung Imaging in Acute Lung Injury
  • Claire Gordon, MBBS (Hons), BMedSci, Instructor, Medicine-Infectious Diseases: Identifying Tissue Reservoirs for Immune-Mediated Control of Chronic Human Herpes Viruses
  • Adam Griesemer, MD, Assistant Professor, Surgery: Combined Liver and Bone Marrow Transplantation for the Induction of Tolerance to Liver Allografts
  • David Kessler, MD, MSc, RDMS, Assistant Professor, Pediatrics-Emergency Medicine: Improving Lumbar Puncture Success in Infants Using Bedside Ultrasound: A Pilot Randomized Clinical Trial
  • Michael Kluger, MD, MPH, Assistant Professor, Surgery-GI-Endocrine: A Pilot Study to Determine the Safety of Recovered Blood Intended for Auto-transfusion During Pancreatic Cancer Operations
  • Ruth Landau, MD, Professor, Anesthesiology: Perioperative Inflammation as a Cause of Postoperative Delirium
  • Emerson Lim, MD, MS, Assistant Professor, Medicine-Hematology and Oncology: Feasibility of Diffuse Optical Tomography (DOT) in Prostate Cancer Detection and Risk Assessment
  • Sander Markx, MD, Assistant Professor, Psychiatry-Molecular Therapeutics: Novel Treatment of Autism Spectrum Disorder Using a Compound That Targets Disease Mechanism in Patients Who Harbor Identical CNTNAP2 Mutations
  • Benjamin Ohlstein, MD, PhD, Assistant Professor, Genetics and Development: Bone Morphogenetic Protein (BMP) Regulation of Drosophila Intestinal Stem Cells
  • Maya K. Rao, MD, Assistant Professor, Medicine-Nephrology: Creating a Comprehensive Nutrition Plan in Patients with Advanced Chronic Kidney Disease: A Pilot Study
  • Carrie Shawber, PhD, Associate Research Scientist, Obstetrics and Gynecology: Characterization and Therapeutic Targeting of Lymphatic Dysfunction in Congenital Chylothorax
  • Andrew Teich, MD, PhD, Assistant Professor, Pathology and Cell Biology: An Analysis of DNA Methylation and Dementia Status in Alzheimer's Disease
  • Danielle Templeton, PhD, Postdoctoral Research Fellow, Medicine-Cardiology: Skeletal Muscle Dysfunction in Diastolic Heart Failure
  • Nina B.L. Urban, MD, MSc, Assistant Professor, Psychiatry-Substance Abuse: Deep Brain Stimulation for Refractory Alcohol Dependence

2013 Irving Institute/CTO Pilot Awardees

  • Alvaro Aytes-Meneses, PhD, Associate Research Scientist, Urology and Herbert Irving Comprehensive Cancer Center (HICCC): A Systems Biology Approach for the Identification of Molecular Drivers of Metastatic Prostate Cancer
  • Lauren Chernick, MD, Assistant Professor of Clinical Pediatrics, Pediatrics-Emergency Medicine: The Texting 2 Initiate (T2I) Study: A Pilot Randomized Controlled Trial Using Text Messaging From the Pediatric Emergency Department to Increase Contraception Initiation Amongst Adolescent Females at High Pregnancy Risk
  • Remi J. Creusot, PhD, Assistant Professor, Medicine-Immunology: Mapping Ectopic Expression of Islet Antigens in Tolerogenic Cell Subsets From Human Peripheral Lymphoid Tissues
  • Raimon Duran-Struuck, DVM, PhD, Assistant Professor, Surgery-Translational Immunology: Induction of Solid Organ Tolerance Through Bone Marrow and Regulatory T Cell Transplantation
  • Annika Hofstetter, MD, PhD, MPH, Assistant Clinical Professor, Pediatrics: A Multilevel Approach to Understanding and Optimizing Influenza and Pneumococcal Vaccination of Children with Chronic Medical Conditions
  • Ian Kronish, MD, MPH, Assistant Professor, Medicine-Behavioral Cardiology: Using Mobile Health to Improve Medication Adherence in a Social Network
  • Amir Levine, MD, Associate Research Scientist, Neuroscience: Advancing the Treatment of Pediatric Anxiety Disorders by Predicting Treatment Response Through Biocellular Markers and Sequencing Technology
  • Anthony Pinto, PhD, Assistant Professor of Clinical Psychiatry, Psychiatry-Clinical Therapeutics: Neural Mechanisms Underlying Self‐Control
  • Simone Sanna-Cherchi, MD, Associate Research Scientist, Medicine-Nephrology: Identification of Recessive Alleles Underlying Genomic Disorders of the Kidney and Urinary Tract Development
  • P. Christian Schulze, MD, PhD, Associate Professor, Medicine: Serial Analysis of Myocardial Metabolism by Positron Emissions Tomography (PET) in Patients with Heart Failure Undergoing Ventricular Assist Device Implantation
  • Markus David Siegelin, MD, Assistant Professor, Pathology and Cell Biology: Preclinical translational studies on a novel potent combined therapy for malignant glioma
  • Nadejda Tsankova, MD, PhD, Assistant Professor, Pathology and Cell Biology: Epigenetic Mechanisms of EGFR Dysregulation in Human Gliomagenesis and Glioma Progression; a Possible Role for Mutant IDH1
  • Daniel S. Tsze, MD, MPH, Assistant Professor of Clinical Pediatrics, Pediatrics-Emergency Medicine: Optimal Volumes of Administration for Intranasal Midazolam in Children
  • Raksha Urs, PhD, Associate Research Scientist, Ophthalmology: Ultrasound Microbubble Mediated Trans-Epithelial Delivery of Riboflavin for Corneal Cross-Linking Therapy
  • Elaine Wan, MD, Instructor, Medicine-Cardiology: Roles of Vascular Ion Channels in Heart Failure
  • Yanghee Woo, MD, Instructor, Surgery: Prevention and attenuation of gastric tumorogenesis through denervation

2012 Irving Institute/CTO Pilot Awardees

  • Brooke Aggarwal, EdD, MS, Associate Research Scientist, Medicine-Cardiology: A Randomized Pilot Study of an ICD/Heart Failure Patient - Family Caregiver Dyad Intervention
  • Armin Alaedini, PhD, Assistant Professor, Medicine: Proteomic Analysis of the Antibody Response in Non-Celiac Gluten Sensitivity
  • Kara L. Bickham, MD, Associate Research Scientist, Medicine: Development of Respiratory Immunity in Infants and Children
  • Angelo B. Biviano, MD, MPH, Esther Aboodi Assistant Professor of Clinical Medicine, Medicine: Utility of Atrial Electrogram Signal Analysis in Patients Undergoing Percutaneous Catheter Ablation for Atrial Fibrillation
  • Adi Cohen, MD, MHS, Assistant Professor of Clinical, Medicine: The Growth Hormone Axis and Bone Turnover in Premenopausal Women with Idiopathic Osteoporosis
  • Eileen Connolly, MD, PhD, Assistant Professor, Radiation Oncology: Enhancing the Radiation Sensitivity of Triple Negative Breast Cancer through Akt Inhibition
  • Isaac George, MD, Assistant Professor, Surgery: Dysregulation of TGF-β Family Signaling May Predict Patterns of Disease in Dilated Cardiomyopathy and Aortic Aneurysm Formation
  • Ragy R. Girgis, MD, Assistant Professor, Psychiatry-Neuroscience: The Metabotropic Glutamate Receptor 5 (mGluR 5) in Schizophrenia: A PET Study with [11C]ABP688
  • David J. Lederer, MD, MS, Herbert Irving Assistant Professor, Medicine: Obesity, Inflammation, and Lung Injury after Lung Transplantation
  • Guoxhia Liu, PhD, Associate Research Scientist, Medicine-Cardiology: Treatment of Cardiovascular Diseases Using Novel Soluble Epoxide Hydrolase Inhibitors
  • Jose Moron-Concepcion, PhD, Assistant Professor of Clinical Anesthesiology, Anesthesiology: Glial Modulators: Novel Therapeutic Interventions for Pain and Opioid Abuse
  • Kimberly Noble, MD, PhD, Assistant Professor, Pediatrics: Childhood Social Disadvantage, Brain Development, and Verbal Skills
  • Cesare Russo, MD, Associate Research Scientist, Medicine-Cardiology: Subclinical Cardiac Dysfunction, Myocardial Inflammation and Perfusion in Patients with Rheumatoid Arthritis
  • Pejman Sehatpour, PhD, Associate Research Scientist, Psychiatry: tDCS and Sensory-Perceptual Dysfunction in Schizophrenia
  • Bekir Tanriover, MD, Assistant Professor of Clinical Medicine, Medicine: Effect of Living Kidney Donation on Metabolic State and Insulin Sensitivity
  • Waichi Wong, MD, Assistant Professor of Clinical Medicine, Medicine: Is Neutropenia Post-Liver Transplant Associated with T-Cell Chimerism? A Possible Opportunity for Tolerance Induction

2011 Irving Institute/CTO Pilot Awardees

  • Susanne E. Ahmari, MD, PhD, Assistant Professor of Clinical Psychiatry, Psychiatry: Using Optogenetic Technology to Test Involvement of Orbitofrontal Cortex Pathology in Obsessive Compulsive Disorder
  • Anjali Ganda, MD, MS, Instructor in Clinical Medicine, Medicine: HDL-Mediated Cholesterol Efflux, Monocytosis, and Accelerated Atherosclerosis in Patients with Chronic Kidney Disease
  • Laura Geraldino, MD, Clinical Instructor, Medicine: Rheumatology: Anti-Citrullinated Peptide Antibodies: Surrogate Markers of Cardiac Dysfunction and/or Atherosclerosis in Rheumatoid Arthritis Patients?
  • Kevin Kalinsky, MD, Instructor in Clinical Medicine, Medicine: The Investigation of the Novel AKT Inhibitor on Magnetic Resonance Spectroscopy in Women with Operable Invasive Breast Cancer
  • Joshua Kantrowitz, MD, Assistant Professor of Clinical Psychiatry, Psychiatry: NMDA and Cognitive Remediation in Schizophrenia
  • Krzysztof Kiryluk, MD, MS, Instructor in Clinical Medicine, Medicine: Genetic Causes of IgA Nephropathy by Next Generation Sequencing
  • David K. Leung, MD, PhD, Assistant Professor of Clinical Radiology, Radiology: Functional Imaging in Pancreatic Cancer: Investigations of a New Tumor Specific PET Radiotracer
  • Julian Mackay-Wiggan, MD, MS, Assistant Clinical Professor, Dermatology: A Randomized Placebo Controlled Study of IL Triamcinolone Acetonide in the Treatment of Alopecia Areata and Investigation of Biomarkers in Patients with Alopecia Areata
  • Catherine Monk, PhD, Assistant Professor of Clinical Psychology, Psychiatry: Electrophysiological Development in Toddlers of Adolescent Mothers: Association with Maternal Antenatal Stress and Nutrition
  • John P. Morrow, MD, Assistant Professor, Medicine-Cardiology: PKG Activation to Protect Against Arrhythmias in Animal Models of LQTS and Diabetic Cardiomyopathy
  • Gabrielle Page-Wilson, MD, Instructor, Medicine: Treatment of Hyperprolactinemia with the Non-Ergoline Dopamine Agonist Ropinirole - A Dose Escalation Study of Efficacy and Tolerability
  • Paul J. Planet, MD, PhD, Postdoctoral Clinical Fellow, Pediatrics: Adaptation of MRSA to Ethanol-Based Microbicides: Impact of a Novel Alcohol Dehydrogenase (AdhC) on Epidemiology and Virulence
  • Tara M. Randis, MD, Assistant Professor, Pediatrics: New Approaches to Prevention of Neonatal Group B Streptococcal Disease
  • Igor Shuryak, MD, PhD, Associate Research Scientist, Center for Radiological Research: Low Dose Prophylactic Mammary Irradiation to Reduce Contralateral Second Breast Cancer Risks
  • Douglas M. Sproule, MD, Instructor, Neurology: Body Composition, Nutrition and Energy Utilization in Spinal Muscular Atrophy
  • Anette Wu, MD, MPH, Associate Research Scientist, Medicine-Oncology: Induction of Liver Allograft Tolerance through Bone Marrow Transplantation: Translational Pre-clinical Pilot Study in Monkeys

2010 Irving Institute/CTO Pilot Awardees

  • Julian Abrams, MD, MS, Assistant Professor of Clinical Medicine, Medicine: Digestive and Liver Diseases, Use of a Gastrin-Receptor Antagonist for Chemoprevention in Patients with Barrett's Esophagus
  • Emilio Arteaga-Solis, MD, PhD, Assistant Professor, Pediatrics: A Mechanistic Link of Obesity-Associated Asthma: Leptin Mediates Lung Physiology via a Central Nervous System Relay
  • Gudrun Aspelund, MD, Assistant Professor, Surgery: Interval Appendectomy Compared with Nonoperative Treatment for Perforated Appendicitis in Children
  • Jae H. Choi, MD, MS, Assistant Professor, Neurology: Non-Invasive Quantification of Cerebral Autoregulation in Patients with Acute Ischemic Stroke and Increased Risk for Ischemic Stroke
  • Christoph Kellendonk, PhD, Assistant Professor of Pharmacology, Psychiatry: A Translational Study: Methylphenidate Effects on Frontostriatal Circuits in ADHD
  • Laura B. McIntire, PhD, Associate Research Scientist, Pathology and Cell Biology: In Vivo Efficacy of a New Class of CNS Targeted Amyloid Lowering Compounds
  • Jose F. Morales, PhD, Associate Research Scientist, Joint Center for System Biology: The Lymphoid Malignancy Phenome Score
  • Nicholas J. Morrissey, MD, Assistant Professor, Surgery, Assessment of Vascular Disease Frequency, Risk Factors, and Outcomes in Hispanic Patients
  • Andrew B. Munkacsi, PhD, Associate Research Scientist, Pediatrics: Inhibition of Histone Deacetylase as a Treatment of Neurodegeneration and Defective Cholesterol Transport in Niemann-Pick Type C Disease
  • Hatice Duygu Onat, PhD, Associate Research Scientist, Medicine: Type 2 Diabetes and Vascular Disease in Human Studies: The Interplay of Systemic Endothelial Activation and Inflammatory Cell Stress During Disease Progress
  • David C. Riley, MD, MS, Assistant Clinical Professor of Medicine, Medicine: Emergency Department Real Time Cannulation of the Internal Jugular Vein on the First Attempt: Ultrasound-Guided Short-Axis vs. Long-Axis Method
  • P. Christian Schulze, MD, PhD, Assistant Professor, Medicine: Effects of Glutamine and Fish Oil on Muscle Function in Heart Failure (GlutFish-HF)
  • Aviva Bracha Sopher, MD, MS, Postdoctoral Clinical Fellow, Pediatrics: Body Composition and Metabolic Manifestations of Insulin Resistance in Adolescents with Polycystic Ovary Syndrome: Ectopic Fat Deposition and Metabolic Markers
  • Krishna Surapaneni, MD, MPH, Postdoctoral Clinical Fellow, Radiology: In Vivo MRI Immune Cell Tracking and Quantification of Target Natural Killer (NK) Cell Immunotherapy for Poor Risk Childhood B-Cell (CD20+) Lymphoma/Leukemia
  • Arun Swaminath, MD, Assistant Professor of Clinical Medicine, Medicine-Digestive and Liver Diseases: The Use of Positron Emission Tomography, Inflammatory Makers, and Intestinal Stem Cell Concentration to Predict Response to Treatment of Small Bowel Crohn's Disease with Biologic Therapy: A Pilot Study
  • Edward Thorp, PhD, Associate Research Scientist, Medicine: Soluble MER in CVD

2009 Irving Institute/CTO Pilot Awardees

  • Jason B. Carmel, MD, PhD, Instructor, Neurology: Transcranial Direct Current Stimulation to Strengthen Corticospinal Connections and Promote Recovery After Injury
  • Neil R. Gleason, MD, Instructor, Anesthesiology: GABAa Receptors on Human Vascular Smooth Muscle Influence Blood Pressure
  • Kara J. Gross, MD, Assistant Professor, Pediatrics: Serotonin Depletion in the Prevention and Treatment of Inflammatory Bowel Diseases and Necrotizing Enterocolitis
  • Anupam B. Kharbanda, MD, Assistant Professor of Clinical Pediatrics, Pediatrics-Emergency Medicine: Biomarker Profiling for Pediatric Appendicitis
  • Judith Korner, MD, PhD, Associate Professor of Medicine, Medicine: Changes in Gut Hormones and Neural Control of Food Intake in Hypothalamic Obesity
  • Antonio Mantovani, MD, PhD, Associate Research Scientist, Psychiatry: Modulation of Premotor and Motor Circuits in Obsessive-Compulsive Disorder (OCD): A Transcranial Magnetic Stimulation (TMS) and Magnetic Resonance Spectroscopy (MRS) Study
  • Igor Matushansky, MD, PhD, Assistant Professor of Medicine, Medicine: Oncology, Implementing and Imaging Epigenetic Based Differentiation Therapy for Solid Tumors
  • June Wu, MD, Assistant Professor of Surgery, Surgery: The Role of Notch3 Signaling in the Pathogenesis of Hemangiomas

2008 Irving Institute/CTO Pilot Awardees

  • Hyunmi Choi, MD, MS, Assistant Professor of Clinical Neurology, Neurology: The Role of Coenzyme Q10 in Pathogenesis and Therapy of Intractable Temporal Lobe Epilepsy with Hippocampal Sclerosis
  • Jan Claassen, MD, PhD, Assistant Professor, Neurology: Impact of Electrographic Seizures and Periodic Epileptiform Patterns on Neuronal Function and Outcome in Brain Injured Patients
  • Raphael Clynes, MD, PhD, Assistant Professor of Medicine, Medicine: Induction of Tumor Immunity in Untreated CLL Patients Through the Use of Rituximab and Denileukin Diftitox
  • Charles J. DiMaggio, PhD, Assistant Professor of Clinical Epidemiology, Anesthesiology: Retrospective Cohort Analysis of the Effects of Anesthesia on Behavioral and Developmental Disorders in Young Children
  • Barry Hudson, PhD, Associate Research Scientist, Surgery: Preoncology: The Soluble Splice Variant of RAGE is a Protective Mechanism Against Tumorigenesis and Metastasis
  • Daniel Kass, MD, Instructor in Clinical Medicine, Medicine: Targeting the MetAP2 Pathway in Pulmonary Arterial Hypertension
  • Marilyn Morris, MD, MPH, Assistant Professor of Clinical Pediatrics, Clinical Care - Ethics: Pediatric Minimal Risk Research: A Parental Perspective
  • David Paik, MD, Associate Research Scientist, Ophthalmology: Development of a Pharmacologic Alternative to Therapeutic Corneal Cross-Linking Using Aliphatic Beta-Nitro Alcohols (Proprietary Columbia University Technology)
  • Gissette Reyes, MD, Instructor, Medicine: Preventive Medicine and Nutrition: Lipoprotein Metabolism in Obese Postmenopausal Metabolically Healthy Obese Versus Metabolically Abnormal Obese Women
  • Mishaela Rubin, MD, Assistant Professor of Clinical Medicine, Medicine: Endocrinology, Osteocalcin and Glucose Homeostasis in Hypoparathyroidism
  • Bret Rutherford, MD, Postdoctoral Clinical Fellow, Pediatrics: Expectancy Effects and Treatment of Depression: Cognitive and Neural Mechanisms
  • Aaron Turkish, MD, Assistant Professor of Pediatrics, Pediatrics-Developmental Drugs: Development of a Novel Murine Model of Skin Disease

2007 Irving Institute/CTO Pilot Awardees

  • Richard C. E. Anderson, MD, Assistant Professor of Neurological Surgery, Neurology: Identification of CD24 as a Target for Antibody-Based Immunotherapy for Pediatric Medulloblastoma
  • Raphael Clynes, MD, PhD, Assistant Professor of Medicine, Medicine, Converting Passive to Active Immunity: Correlation of HER-2 Specific T Cell Responses and Clinical Outcomes in Patients Treated with Traztuzumab
  • Andrew Einstein, MD, PhD, Assistant Professor of Clinical Medicine, Medicine: Cardiology, Effects of Patient Habitus and Breast Shielding on Radiation Dose in Coronary Computed Tomography Angiography
  • Charles W. Emala, MD, Associate Professor, Anesthesiology: GABAa- Mediated Relaxation of Airway Smooth Muscle
  • Adolfo Ferrando, MD, PhD, Assistant Professor of Pediatrics and Pathology, Pediatrics: Treatment of T-ALL with Gamma-Secretase Inhibitors
  • Ali Gharavi, MD, Assistant Professor, Medicine: Genetic Studies of Acute Renal Allograft Rejection
  • Seunghee Kim-Schulze, PhD, Associate Research Scientist, Surgery: Targeting Inhibitory Receptor ILT3 in Immunotherapy
  • Robert Klitzman, MD, Associate Professor of Clinical Psychiatry, Sociomedical Sciences: Views and Approaches Toward Pre-Implantation Genetic Diagnosis (PGD) and Barriers to its Use Among Providers and Patients
  • Laurel Mayer, MD, Irving Assistant Professor, Psychiatry: Understanding the Neural Circuitry of Eating Disorders
  • Arielle D. Stanford, MD, Assistant Professor of Clinical Psychiatry, Psychiatry: Delineating and Modulating the Circuitry of Volition: Treatment Development in Schizophrenia
  • Drew V. Tortoriello, MD, Assistant Professor, Obstetrics and Gynecology: Long-acting Mullerian Inhibiting Substance Analogue for the Treatment of Endometriosis
  • Qin Wang, PhD, Assistant Professor of Clinical Pathology, Surgery: Endothelial Cell Injury During High Dose IL-2 Immunotherapy
  • William Whang, MD, MS, Assistant Professor of Clinical Medicine, Medicine: Cardiology, Pilot Studies of Ventricular Remodeling, Microvolt t-wave Alternans and Sudden Cardiac Death
  • Ismee Williams, MD, MS, Assistant Professor of Clinical Pediatrics, Pediatrics: Endocrinology, The Impact of Congenital Heart Disease on Fetal and Neonatal Neurologic Structure and Function
  • Michael Yin, MD, MS, Assistant Professor of Clinical Medicine, Medicine-Infectious Diseases: Development and Validation of a Multiplex PCR Assay for Rapid Diagnosis of Ventriculostomy Related Infections
  • Yi-Hao Yu, MD, PhD, Assistant Professor, Medicine: Using Dietary Leucine Supplementation to Modify Cardiometabolic Risk Factors in Overweight and Obese Adult Human Subjects