Trial Innovation Network (TIN)

The Trial Innovation Network is a national, collaborative, clinical trial network focused on operational innovation and excellence that leverages the expertise and resources of the CTSA Program. It was developed to address critical roadblocks in clinical trials and accelerate the translation of novel interventions into life-saving therapies. The goal of the Trial Innovation Network is to be a national laboratory to study, understand, and innovate the process of conducting clinical trials. Trials are conducted across all areas of medicine.

Learn More About the Trial Innovation Network

Trial Innovation Network Hub Liaison Team

The Trial Innovation Network Hub Liaison Team at the Irving Institute helps Columbia University Irving Medical Center (CUIMC) clinical trialists and investigators develop, fund, and implement clinical trials in the most efficient manner.

As key partners of the national Trial Innovation Network, our liaison team plays an integral role by:

  • Encouraging faculty and investigators to generate ideas for trials
    • Prior trial topics have included: Antihypertensive Medications and Chronotherapy, Diflunisal for Transthyretin Amyloid Cardiomyopathy, and Vaginal Progesterone in Recurrent Preterm Delivery
  • Providing input before protocols are submitted to the network and to NIH for funding
    • The Hub team worked with an investigator who now is the PI of a NIH funded Metformin and Alzheimer’s Prevention (MAP) trial
  • Helping to build a national infrastructure to conduct clinical trials better, faster, and more cost-effectively


The Trial Innovation Network Hub Liaison Team provides support through:


  • Mitchell Elkind, MD

    Medical Director

    Headshot of Mitchell Elkind.
  • Soumitra Sengupta, PhD

    Director of Informatics

    Headshot of Soumitra Sengupta.
  • Linda Busacca

    Project Manager

Hub Liaison Team

Carmen Castillo , Recruitment Coordinator

Ying Cheung, Biostatistics Specialist

Helen Kim, Contract Specialist

Jianhua Li, Data Navigator

Michelle McClave, Associate Director, Programs and Communication

Rudina Odeh-Ramadan, Contract Specialist

Chunhua Weng, Co-Director